Calcipotriol is a vitamin-D derivative, also known as calcipotriene (Brand Name: Dovonex). It's used to treat Psoriasis, and while it is effective for most Psoriasis patients, its effectiveness is limited. It will reduce the scaliness and patchiness of Psoriasis, but it will not get rid of the red patches. It's also an effective treatment for Morphoea, Palmoplantar pustulosis, Ichthyosis, Keratoderma, Grover´s disease, Hailey-Hailey disease, Pityriasis rubra pilaris, Acanthosis nigricans, and Epidermal naevi. For Psoriasis, to get the best effect, Calcipotriol is often used with other medications like topical steroids, Acitretin, or Salicylic acid.
Calcipotriol is available as an ointment, cream and scalp solution. It can be applied twice daily to plaque Psoriasis on the body or scalp (but not the face). Improvement is usually seen within two weeks. It is typically more effective than corticosteroids alone.
Side effects are rare and mild, but may include red, dry and itchy skin around the treated area. Avoid use on the fact, as it may sting or cause irritation.
Notes of Precaution
* Calcipotriol is poisonous, so it should be kept out of the reach of children and pets.