Fordyce Angiokeratoma

Key Points
Benign growth which typically affects the genital area
Consists of elevated lesions which are dark blue or black in color and may be accompanied by scaling

Fordyce Angiokeratoma is a type of growth which typically affects the genital area. The condition consists of elevated lesions which are dark blue or black in color and may be accompanied by scaling of the overlying skin. Lesions may be solitary or occur in great numbers (100+), and are most commonly found on the scrotum in men and the labia in women. Lesions may also occur on the shaft of the penis, the inner thigh and on the lower part of the abdomen. The condition is typically asymptomatic, although bleeding may occur if the area is abraided.

The exact cause of Fordyce angiokeratomas is unknown. The condition typically develops in adulthood, and is far more common in men than women. In some cases younger persons may be affected, in which case lesions may be smaller in size and red in color, and not accompanied by scaling.

Differential Diagnosis (Other conditions with similar appearance)

Fabry Syndrome
Nevi, melanocytic
Cherry Hemangioma
Petechial Angioma
Granuloma pyogenicum
Squamous cell carcinoma
Malignant Melanoma
Warts, Genital

Diagnosis
Key Points
Diagnosis based on examination of the affected area
Skin biopsy may be performed to confirm diagnosis and rule out other conditions

Fordyce Angiokeratoma is usually diagnosed based on examination of the affected area. A skin biopsy may be performed to confirm the diagnosis and to rule out similar appearing conditions.

Treatment
Condition is benign, therefore treatment is not typically required
Lesions should be biopsied if there is consideration for possible malignancy
*If required, treatment consists of surgical removal or destruction of the lesion

Fordyce angiokeratomas are benign lesions, and therefore treatment is not typically required. In cases where lesions resemble malignant conditions (Melanoma), lesions should always be biopsied. If treatment becomes necessary due to bleeding or cosmetic concerns, removal via surgical excision, laser therapies, Cryotherapy or electrocautery is the preferred method.