*Rare type of epidermal nevus which typically affects the legs
*Caused by a defect in the ectoderm in the embryonic stage
*Consists of inflamed, red lesions which are warty and form in a linear pattern, and are accompanied by itching, dryness, or scaling
Inflammatory linear verrucous epidermal nevus, or ILVEN, is a rare type of epidermal nevus which typically appears on one leg, and may extend to the buttocks and/or foot. The condition consists of inflamed, red lesions which are warty and form in a linear pattern. Additionally, the condition is accompanied by severe itching, and lesions may experience dryness or scaling.
ILVEN is caused by a defect in the ectoderm, the part of the embryo which forms the skin and neural tissues. While the condition may be congenital in some cases, it typically appears after birth, before the age of 5, and is slightly more common in females. In very rare cases, the defect may also cause internal disorders affecting the brain, eyes and skeleton.
Differential Diagnosis (Other conditions with similar appearance)Acrokeratosis verruciformis of Hopf
Lichen Simplex Chronicus
Keratosis Follicularis (Darier disease)
*Initial diagnosis based on the characteristic appearance of the affected area
*Laboratory tests will be performed to confirm diagnosis and rule out other conditions
ILVEN is initially diagnosed based on the characteristic appearance of the affected area. Laboratory testing will be performed to confirm the diagnosis and to rule out similar appearing conditions.
*No cure for the condition exists
*Treatment consists of managing symptoms
No cure for ILVEN exists. The primary goal of treatment is the management of symptoms. Topical steroids and emollients may be prescribed for itching, while Calcipotriol may assist in preventing dryness in the affected area.