Infliximab

Infliximab

Chris Schach

Author Bio -

Uses

* Infliximab is used to relieve the symptoms of certain autoimmune disorder such as psoriasis, Crohn's disease, ankylosing spondylitis, psoriatic arthritis, rheumatoid arthritis and ulcerative colitis.

Infliximab (Trade name: Remicade) is a drug classified as a tumour necrosis factor (TNF) blocker. It works by blocking a substance in the body that causes inflammation. It is used to treat psoriasis, Crohn's disease, ankylosing spondylitis, psoriatic arthritis, rheumatoid arthritis and ulcerative colitis. While Infliximab may help control symptoms, it does not cure skin conditions.

Infliximab has also been shown to help patients with other inflammatory skin conditions like hidradenitis suppurativa, pyoderma gangrenosum and pemphigus vulgaris.

Dosing

For psoriasis and psoriatic arthritis, infliximab is administered by intravenously under supervision over a two hour period and repeated every two to six weeks.

Side effects

Although side effects are mild and generally rare, you should notify your doctor if you experience persistent side effects including coughing, nausea, vomiting, stomach pain, headache, fever, fatigue and muscle weakness, runny nose, back pain, white patches in the mouth, vaginal itching, burning, and pain or other signs of a yeast infection, flushing, and/or heartburn.

Injections may cause serious allergic reactions during an infusion and for 2 hours afterward, and a doctor should monitor you during this period for serious reactions. Medications may be given to prevent or treat serious reactions to Infliximab.

Notes of Precaution

* Notify your doctor if you are allergic to infliximab injection, any medications made from murine proteins, or any other medications.

* Because it suppresses the immune system, you should be tested for tuberculosis or other infections before an Infliximab injection.

* Notify your doctor if have or have ever had congestive heart failure, central nervous system disorders, seizures, kidney or liver failure, or if you are pregnant or breastfeeding. Injections are not advisable in such situations.

* Notify your doctor of any recent or planned vaccinations before an injection.
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